منابع مشابه
Hypolipidemic effect of type Ia antiarrhythmic agents in postinfarction patients.
BACKGROUND Elevated levels of cholesterol and apoprotein B (apo B), the essential carrier protein for low density lipoprotein, are major lipid risk factors for premature coronary disease. Antiarrhythmic agents are frequently prescribed to patients with coronary heart disease and associated cardiac arrhythmias. As part of another study, we retrospectively investigated the effect of antiarrhythmi...
متن کاملInhibition of Hepatic Acetyl Coenzyme by Hypolipidemic Agents*
The effects of two hypolipidemic agents, 2-methyl-2-[p(1,2,3,4-tetrahydro-l-naphthyl)-phenoxy]propionate and ethyl 2-(p-chlorophenyl)-2-methylpropionate, on the activity of a highly purified preparation of acetyl coenxyme A carboxylase, obtained from chicken livers, were studied. Both compounds are inhibitors of acetyl-CoA carboxylase, but they have no inhibitory effect on a number of other enz...
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The simple boronated bases, e.g. cytosine, adenine and guanine, containing no sugar residues retained good pharmacological activity as hypolipidemic, anti-neoplastic and anti-inflammatory agents in mice at 8 mg/kg. Their activities were generally identical to their respective nucleoside derivatives. Interestingly the boronated acyclovir derivative was a very potent hypolipidemic agent achieving...
متن کاملHypolipidemic property of ascofuranone.
Ascofuranone significantly reduced serum lipid levels of rats fed with normal diet 6 hours after a single oral administration of 108 mg/kg. Whenthe antibiotic was orally given for consecutive 10 days to normolipidemic rats, the treatment resulted in marked reduction of serum cholesterol, triglycerides, phospholipids and free fatty acids without affecting organ weight gain, serum total protein, ...
متن کاملDifferent Adipose Depots: Their Role in the Development of Metabolic Syndrome and Mitochondrial Response to Hypolipidemic Agents
Adipose tissue metabolism is closely linked to insulin resistance, and differential fat distributions are associated with disorders like hypertension, diabetes, and cardiovascular disease. Adipose tissues vary in their impact on metabolic risk due to diverse gene expression profiles, leading to differences in lipolysis and in the production and release of adipokines and cytokines, thereby affec...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1977
ISSN: 0014-5793
DOI: 10.1016/0014-5793(77)80785-0